Colts face their first road test at Tennessee after a 2-0 start that leaned on early offense and clutch special teams. Indy sits as a -3.5 favorite with a -166 money line and a 42.5 over/under, signaling a tight, grind-it-out divisional affair. The win over Denver featured a bold start and late heroics from Shrader and Lutz, while the Titans’ rookie Cam Ward has shown upside but finishing drives remains a work in progress.

Fantasy angles hinge on Ward’s early impact and the Colts’ improving weaponry. If Ward can sustain drives, Tennessee’s ceiling rises; if not, Indy’s defense and kicking game could tilt the balance. This matchup sets up as a pivotal early-season test that could define who controls the division and which players emerge as weekly fantasy starters or sit-downs.

Indy’s two-week surge behind Daniel Jones and Shane Steichen has flipped the script in Indy. A revamped offense, anchored by a healthier line and a top-flight run game, rolled to a 2-0 start and stacked early scoring drives, signaling a potential franchise reset rather than a fluke. Jones has transformed into a poised, efficient playmaker, thriving even under pressure and guiding a revamped Colts attack with confidence and precision.

The off-season gambles—Jones, Bynum, Ward—paired with Lou Anarumo’s defensive tweaks, have re-energized a once-dubious roster. Jones’ red-zone efficiency, decision-making, and ability to exploit blitzes provide solid fantasy fodder, while Jonathan Taylor remains a high-floor, workhorse option. The output invites aggressive expectations, yet the young team remains mindful of the long season ahead.

Miami sits 0-2 after a 33-27 loss to New England, with a short week in Buffalo on deck. The defense leaks points and the offense struggles to sustain drives, raising questions for McDaniel and Grier. Austin Jackson is on IR, widening OL concerns and fantasy risk.

Hill remains the main weapon, but line issues and a tougher schedule temper the ceiling. Tua Tagovailoa must dodge pressure to maximize production, while potential depth options could surface as the line settles before Week 3.